Authors: Ann Clawson Peter E Clayson Mikle South Erin D Bigler Michael J Larson
Publish Date: 2013/07/26
Volume: 45, Issue: 2, Pages: 363-375
Abstract
Little is known about the functional impact of putative deficits in whitematter connectivity across the corpus callosum CC in individuals with autism spectrum disorders ASDs We utilized the temporal sensitivity of eventrelated potentials to examine the interhemispheric transfer time IHTT of basic visual information across the CC in youth with highfunctioning ASD relative to healthy controls We conducted two experiments a visual letter matching experiment n = 46 and a visual picture matching experiment n = 48 and utilized both electrophysiological N1 and P1 amplitudes and latencies and behavioral response times RTs error rates indices of IHTT There were no significant group differences on either experiment for RTs error rates or N1 and P1 latencies suggesting that on basic tasks the timing of information flow across the CC may not be altered in high functioning ASDWe gratefully acknowledge the assistance of Kyle Jamison Whitney Worsham Whitney Ernst and Tiffany Newton in data collection This study was supported by funds from the Brigham Young University College of Family Home and Social Sciences and the Poelman Foundation
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