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Title of Journal: Surg Today

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Abbravation: Surgery Today

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Springer Japan

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DOI

10.1007/bf02039406

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1436-2813

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Hemofiltration for hyperbilirubinemia after left v

Authors: Shigeru Miyagawa Motonobu Nishimura Norihide Fukushima Goro Matsumiya Yuji Fujino Hikaru Matsuda Yoshiki Sawa
Publish Date: 2008/07/31
Volume: 38, Issue: 8, Pages: 747-750
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Abstract

We hypothesized that the use of hemofiltration HF to reduce cytokines may attenuate the hyperbilirubinemia that often develops after left ventricular assist system LVAS implantation Four patients with hyperbilirubinemia after LVAS implantation underwent HF continuously for 7 days Blood samples were collected and the serum concentrations of total bilirubin TBil interleukin IL6 and IL8 were measured We also measured the serum concentrations of IL6 and IL8 in the blood flowing into and out of the filter Two patients had reduced serum concentrations of IL6 IL8 and TBil but the other two did not despite the effective filtration of these cytokines Our findings suggest that the reduction of cytokines by HF may assist in the treatment of hyperbilirubinemia after LVAS placement in some patients

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