Authors: Jean Lubrano Horace Roman Sophie Tarrab Benoit Resch Loïc Marpeau Michel Scotté
Publish Date: 2008/03/27
Volume: 38, Issue: 4, Pages: 293-
Abstract
We retrospectively examined 16 patients who underwent partial liver resection for breast cancer liver metastasis BCLM All patients had been treated with chemotherapy or hormonotherapy or both before referral for surgery We confirmed by preoperative radiological examinations that metastasis was confined to the liver The survival curve was estimated using the KaplanMeier method Univariate and multivariate analysis were conducted to evaluate the role of the known factors of breast cancer survivalThe median age of the patients was 54 years range 38–68 and the median diseasefree interval between the diagnoses of breast cancer and liver metastasis was 54 months range 7–120 Nine major and 7 minor hepatectomies were performed There was no postoperative death The overall 1 3 and 5year survival rates were 94 61 and 33 respectively The median survival rate was 42 months Univariate analysis revealed that hormone receptor status number of metastases a major hepatectomy and a younger age were associated with a poorer prognosis The survival rate was not influenced by the diseasefree interval grade or stage of breast cancer or intraoperative blood transfusions The number of liver metastases was identified as a significant independent factor of survival according to the Cox proportional hazard model P = 004
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