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Title of Journal: Surg Today

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Abbravation: Surgery Today

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Springer Japan

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DOI

10.1002/chin.199733300

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1436-2813

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Diagnostic value of Superscript18/SuperscriptF

Authors: Hiroyuki Yamada Masao Hosokawa Kazuo Itoh Toshinao Takenouchi Yoshihiro Kinoshita Tomohiro Kikkawa Keita Sakashita Shion Uemura Yasunori Nishida Takaya Kusumi Shigeyuki Sasaki
Publish Date: 2013/09/27
Volume: 44, Issue: 7, Pages: 1258-1265
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Abstract

This study investigated the diagnostic accuracy of hybrid positronemission tomography/computed tomography PET/CT for lymph node LN metastasis of esophageal cancer We also investigated the correlation between the size of metastatic nests and the detection by PET/CTTwo hundred and fiftyeight patients with esophageal squamous cell carcinoma who underwent esophagectomy with two or threefield radical lymphadenectomy were analyzed retrospectively We compared the diagnosis of preoperative PET/CT to the postoperative histopathological examination by each anatomical field n = 1231 in all 258 patients The metastatic LNs resected from PET/CT positive fields were classified as belonging to the PET/CTNpositive group n = 229 and those from negative fields as belonging to the PET/CTNnegative group n = 352 The crosssectional areas of metastatic nests were measured in each metastatic LNOf the 1231 fields 275 22  were positive for metastasis including 581 LNs from 408 regional LN stations The sensitivity and specificity of PET/CT examined by each anatomical field were 258 and 978  respectively The median area of metastatic nests was 177 mm2 in the PET/CTNpositive group and 77 mm2 in the PET/CTNnegative group p  0001

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