Authors: Soichiro Kitamura Toshikatsu Yagihara Junjiro Kobayashi Hiroyuki Nakajima Koichi Toda Tomoyuki Fujita Hajime Ichikawa Hitoshi Ogino Takeshi Nakatani Shigeki Taniguchi
Publish Date: 2011/03/23
Volume: 41, Issue: 4, Pages: 500-509
Abstract
Since our bank was first established in Japan in 1990 74 patients have undergone various surgical procedures using homografts We classified them into five groups according to the procedure Group I subcoronary implantation of a homograft aortic valve Group II homograft aortic root replacement for active native or prosthetic endocarditis Group III homograft aortic replacement for mycotic aortic aneurysms or infected grafts Group IV pulmonary homografts in the Ross operation and Group V pulmonary homograft conduits for complex congenital heart diseasesThe 9 to 10year survival rates were good and acceptable respectively for the patients in all five groups The infection recurrence rate was low 8 Cardiac eventfree rates including deaths were 057 in Group I 058 Group in II 075 in Group III 081 in Group IV and 069 in Group V operations The rates of structural homograft deterioration suggest that homografts deteriorate more rapidly after subcoronary implantation than aortic root replacements P = 0058Subcoronary implantation should probably be abandoned for routine aortic valve replacement but the continued use of homografts will provide valuable alternatives for patients with active infectious cardiovascular diseases For the Ross operation pulmonary valve homografts showed good durability
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