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Title of Journal: Surg Today

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Abbravation: Surgery Today

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Springer Japan

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DOI

10.1016/0165-5728(90)90007-a

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1436-2813

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Pouchitis disease activity index PDAI does not p

Authors: Mohei Kohyama Yoshio Takesue Hiroki Ohge Yoshiaki Murakami Fumio Shimamoto Taijiro Sueda
Publish Date: 2009/11/01
Volume: 39, Issue: 11, Pages: 962-
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Abstract

The study included 70 patients undergoing an IPAA For these patients an evaluation by PDAI was performed prospectively at 1–2 years after the ileostomy closure When the symptoms relevant to bowel movement appeared PDAI was evaluated and metronidazole or ciprofloxacin was administered Pouchitis was diagnosed in patients with PDAI scores of 7 or higher The patients whose PDAI score was less than 7 and who responded to antibiotic therapy were defined as treatment responders having disease not diagnosed by PDAI TRNDPDAIPouchitis was diagnosed in 16 of the 70 enrolled patients 229 using the PDAI scoring system Of these 16 patients 11 had acute pouchitis and 5 had chronic pouchitis Twentyone patients whose PDAI score was less than 7 were symptomatic Among them 12 were TRNDPDAI In patients with TRNDPDAI antibiotic treatment resulted in significant improvements in the PDAI score P 0001 and in clinical symptoms P 0001 after treatment

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