Authors: Toshiyuki Kitai Masahiro Kawashima Kenya Yamanaka Kunio Ichijima Hideaki Fujii Susumu Mashima Yasuyuki Shimahara
Publish Date: 2011/08/26
Volume: 41, Issue: 9, Pages: 1219-
Abstract
It has been reported that complete cytoreduction using peritonectomy combined with intraperitoneal chemotherapy improves the prognosis of patients with pseudomyxoma peritonei PMP however this treatment strategy remains controversial especially at nonspecialized institutes because of its high morbidity rateWe reviewed the clinical records of 15 consecutive patients with PMP treated in nonspecialized hospitals and observed by one of us between 1999 and 2010 Cytoreductive surgery was done using peritonectomy procedures with intraperitoneal chemotherapy and was performed with curative intent in accordance with SugarbakerAll patients had mucinous tumors disseminated in the peritoneal cavity Complete cytoreduction was achieved in 12 patients Morbidity was 40 6/15 and mortality was 0 0/15 After a median followup period of 43 months the 12 patients who underwent complete cytoreduction were diseasefree with good quality of life and 1 of the 3 patients who underwent incomplete cytoreduction was alive with diseaseThese findings suggest that peritonectomy with intraperitoneal chemotherapy for PMP can provide prognostic benefit even at nonspecialized hospitals Considering the treatment risk it should ideally be performed at a referral center or at least by an experienced surgeon
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