Authors: Daisuke Iitaka Atsushi Shiozaki Hitoshi Fujiwara Daisuke Ichikawa Kazuma Okamoto Shuhei Komatsu Yasutoshi Murayama Hisashi Ikoma Yoshiaki Kuriu Masayoshi Nakanishi Toshiya Ochiai Yukihito Kokuba Teruhisa Sonoyama Eigo Otsuji
Publish Date: 2012/07/01
Volume: 43, Issue: 5, Pages: 556-561
Abstract
A 57yearold male with lower esophageal cancer underwent subtotal esophagectomy with lymphadenectomy The histopathological diagnosis was poorly differentiated squamous cell carcinoma pT2N1M0 pStageIIB After one course of postoperative adjuvant chemotherapy involving lowdose CDDP/5FU a PET–CT scan obtained 12 months after surgery revealed a solitary liver metastasis in the S2 area The patient then underwent five courses of docetaxel chemotherapy 80 mg/body triweekly and a partial response was observed We also performed radiofrequency ablation RFA after which a complete response was observed Twenty months after surgery we detected local liver recurrence in the same position and performed additional RFA Twentyfour months after surgery a solitary lung metastasis was detected in the left S2 area and the patient was administered five additional courses of docetaxel therapy Subsequently PET–CT revealed growth of lung and liver tumors without recurrence in other areas Twentynine months after surgery we partially excised metastatic liver and lung tumors and no subsequent recurrence has since been detected The prognoses of patients who suffer from esophageal cancer organ recurrence are known to be extremely poor and optimal therapeutic strategies for treating these patients have not been established This longterm survival case suggests that multidisciplinary therapy for the treatment of liver and lung recurrence after esophagectomy is effective
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