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Title of Journal: Surg Today

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Abbravation: Surgery Today

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Springer Japan

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DOI

10.1001/archinte.158.4.405

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1436-2813

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Combined autologous cellular cardiomyoplasty using

Authors: Shigeru Miyagawa Goro Matsumiya Toshihiro Funatsu Masao Yoshitatsu Naozumi Sekiya Shinya Fukui Takaya Hoashi Masatsugu Hori Hideki Yoshikawa Yuzuru Kanakura Jun Ishikawa Katsuyuki Aozasa Naomasa Kawaguchi Nariaki Matsuura Akira Myoui Akifumi Matsuyama Sachiko Ezoe Hidehiro Iida Hikaru Matsuda Yoshiki Sawa
Publish Date: 2009/02/07
Volume: 39, Issue: 2, Pages: 133-136
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Abstract

Myocardial regeneration therapy shows great promise as a treatment for heart failure We recently introduced combined autologous cellular cardiomyoplasty with skeletal myoblasts and bone marrow cells as a treatment for human ischemic cardiomyopathy We report the results of our first clinical trial of this technique used to treat a patient with severe heart failure caused by ischemic cardiomyopathy who was being managed with a left ventricular assist system LVAS After combined cell transplantation the patient showed signs of improved cardiac performance and angiogenesis and reduced fibrosis

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