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Title of Journal: Virus Genes

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Abbravation: Virus Genes

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Springer US

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DOI

10.1016/j.abb.2016.05.019

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1572-994X

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Determination of the full length sequence of a chi

Authors: Kyungil Kang Alan H Icard Erich Linnemann Holly S Sellers Egbert Mundt
Publish Date: 2011/08/31
Volume: 44, Issue: 1, Pages: 45-50
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Abstract

The genomic RNA of a novel chicken astrovirus was determined The full length sequence is 7520 nucleotides and encodes three open reading frames 1a 1b 2 for three proteins The genomic organization was similar to other astroviruses with two exceptions The open reading frame of the RNAdependent RNA polymerase contains its own start codon which is different from other astroviruses described to date providing evidence for a replication mechanism different than what has previously been described for astroviruses Furthermore the stemloop structure located at the potential ribosomal frameshift signal described for other astroviruses has been shown to be a hairpin structure for the novel chicken astrovirus Phylogenic analysis of the full length sequence revealed that this chicken astrovirus formed a branch independent from other astroviruses indicating that this astrovirus is significantly different from astroviruses described to date

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