Authors: Flavio R C da Silva Cíntia Daudt André F Streck Matheus N Weber Ronaldo V Leite Filho David Driemeier Cláudio W Canal
Publish Date: 2015/06/27
Volume: 51, Issue: 1, Pages: 77-84
Abstract
Papillomaviruses are small and complex viruses that belong to the Papillomaviridae family which comprises 39 genera The bovine papillomavirus BPV causes an infectious disease that is characterized by chronic and proliferative benign tumors that affect cattle worldwide Different genotypes of BPVs can cause distinct skin and mucosal lesions and the immunity they raise has low crossprotection This report aimed to genotype BPVs in cattle from Northern Brazil based on nucleotide partial sequences of the L1 ORF Skin wart samples from 39 bovines clinically and histopathologically diagnosed as cutaneous papillomatosis from Acre and Rondônia States were analyzed The results revealed four already reported BPV types BPVs 1 2 11 and 13 nine putative new BPV subtypes and four putative new BPV types as well as two putative new BPV types that were already reported To our knowledge this is the first record of BPVs from the Brazilian Amazon region that identified new possible BPV types and subtypes circulating in this population These findings point to the great genetic diversity of BPVs that are present in this region and highlight the importance of this knowledge before further studies about vaccination are attemptedConselho Nacional de Desenvolvimento Científico e Tecnológico CNPq Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul FAPERGS Coordenação de Aperfeiçoamento de Pessoal de Nível Superior CAPES Fundação de Amparo à Pesquisa do Estado do Acre FAPAC and Propesq/UFRGS supported this study
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