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Title of Journal: Food Sci Biotechnol

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Abbravation: Food Science and Biotechnology

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The Korean Society of Food Science and Technology

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DOI

10.1007/bf01726833

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ISSN

2092-6456

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Antifungal activity and action mode of pinocembrin

Authors: Litao Peng Shuzhen Yang Yun Jiang Cheng Feng Chen Siyi Pan Gang Fan
Publish Date: 2012/12/31
Volume: 21, Issue: 6, Pages: 1533-1539
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Abstract

The antifungal activity and possible mode of action of pinocembrin isolated from propolis against Penicillium italicum were investigated Pinocembrin exhibited strong antifungal activity against P italicum in a dosedependent manner Respiration rates of P italicum during spore germination and mycelial growth were significantly inhibited when exposure to pinocembrin The respirations of mitochondria in state 2 and state 3 from mycelia were significantly inhibited in the presence of this compound The phosphorylated adenosine nucleotides levels in hyphae of P italicum treated with pinocembrin were significantly low and energy charge value became unstable Unltrastructure of hyphae was seriously damaged with pinocembrin incubation for 24 h which was further confirmed by the increase of relative ionic leakage and soluble protein loss of P italicum mycelia treated with pinocembrin It was concluded that pinocembrin inhibited the mycelial growth of P italicum by interfering energy homeostasis and cell membrane damage of the pathogen Pinocembrin would be a promising bioactive compound for treatment of P italicum infections on postharvest citrus fruit

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