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Title of Journal: Food Sci Biotechnol

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Abbravation: Food Science and Biotechnology

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The Korean Society of Food Science and Technology

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DOI

10.1016/0006-8993(81)90274-2

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2092-6456

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Antiinflammatory effect of birsonimadiol from see

Authors: Rosa Martha Pérez Gutiérrez
Publish Date: 2016/04/30
Volume: 25, Issue: 2, Pages: 561-566
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Abstract

The new compound identified as 16α23αdihydroxy3β28β30αtriacetoxyolean12ene named birsonimadiol BIR was isolated from Byrsonima crassifolia seeds using activityguided fractionation and structural elucidation was achieved based on extensive analysis of spectroscopic data Effects of BIR on acute and chronic phases of inflamation were studied in edema induced using formaldehyde 12Otetradecanoylphorbolacetate TPAinduced ear edema meloperoxidase activity and histamine carrageenan cotton pellet granuloma and adjuvantinduced arthritis Antiinflammatory activities of BIR were indicated based on reduction of edema levels induced in models of inflammation Antiinflammatory activities were also investigated in murine macrophage RAW2647 cells BIR suppressed production of nitric oxide NO and prostaglandin E2 PGE2 decreased gene expression of cyclooxygenase2 COX2 inhibited tumor necrosis factor TNFα and protein secretion of interleukin IL6 Triterpene was an effective topical antiinflammatory agent in experimental models of acute and chronic dermatitis and can be used in inflammatory disorders

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  8. Modulation of intestinal microbiota in mice by kefir administration
  9. Chromatic characteristics and anthocyanin compositions of cabernet sauvignon wines: Influence of indigenous Saccharomyces cerevisiae strains in Ningxia, China
  10. Effect of heat and autoclave on allergenicity of porcine serum albumin
  11. Protease and γ-glutamyltranspeptidase activities of bacillus spp. isolated from rice straw
  12. Anti-inflammatory activity of ethanolic extract of Sargassum sagamianum in RAW 264.7 cells
  13. Anti-oxidant and anti-inflammatory properties of methanol extracts from various crops
  14. Effects of ozone on the cytomembrane and ultrastructure of Pseudomonas aeruginosa
  15. Antidiabetic andantioxidant properties, and α-amylase and α-glucosidase inhibition effects of triterpene saponins from Piper auritum
  16. Stress tolerance and physicochemical properties of encapsulation processes for Lactobacillus rhamnosus in pomegranate ( Punica granatum L.) fruit juice
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