Authors: Shelby A Skoog Anirudha V Sumant Nancy A MonteiroRiviere Roger J Narayan
Publish Date: 2012/04/03
Volume: 64, Issue: 4, Pages: 520-525
Abstract
Ultrananocrystalline diamond UNCD exhibits excellent biological and mechanical properties which make it an appropriate choice for promoting epidermal cell migration on the surfaces of percutaneous implants We deposited a ~150 nm thick UNCD film on a microporous silicon nitride membrane using microwave plasma chemical vapor deposition Scanning electron microscopy and Raman spectroscopy were used to examine the pore structure and chemical bonding of this material respectively Growth of human epidermal keratinocytes on UNCDcoated microporous silicon nitride membranes and uncoated microporous silicon nitride membranes was compared using the 345dimethylthiazol2yl25diphenyltetrazolium bromide MTT assay The results show that the UNCD coating did not significantly alter the viability of human epidermal keratinocytes indicating potential use of this material for improving skin sealing around percutaneous implants
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