Authors: Nicola Maffulli Mattia Loppini Umile Giuseppe Longo Vincenzo Denaro Francesco Oliva
Publish Date: 2013/02/15
Volume: 37, Issue: 5, Pages: 819-826
Abstract
The aim of the study was to compare clinical and radiographic outcomes of openingwedge high tibial osteotomy HTO augmented with either xenograft or tricalcium phosphate spacer for the management of medial compartment osteoarthritis OA with genu varumBetween 2004 and 2007 we prospectively enrolled 52 patients with medial compartment knee OA who underwent openingwedge HTO fixed with locking Puddu plate and xenograft n = 26 or nonlocking Puddu plate and tricalcium phosphate spacer n = 26 The alignment of the lower limb was assessed by measuring the hipkneeankle HKA angle Clinical outcomes were assessed with the Knee Society Score Western Ontario and McMaster Universities Osteoarthritis Index SF36 and European Quality of Life5 Dimensions scale All patients were followed up at six weeks and at three six 12 and 24 months postoperatively Clinical outcomes were assessed preoperatively and at 24 months postoperativelyAll clinical scores improved significantly in both groups after surgery without any significant difference between the two groups Immediately after surgery the HKA angle went from 91 ± 52° in varus to 31 ± 48° in valgus P = 001 in the xenograft group and from 85 ± 59° in varus to 34 ± 42° in valgus P = 001 in the tricalcium phosphate group At the last followup the tricalcium phosphate group showed a significant loss of correction P = 003HTO performed with xenograft locking plate and tricalcium phosphate nonlocking plate constructs showed good clinical outcomes However the xenograft locking plate construct is superior to the tricalcium phosphate spacer nonlocking plate to prevent the loss of correction in the middle term
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