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Title of Journal: International Orthopaedics SICOT

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Abbravation: International Orthopaedics

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Springer Berlin Heidelberg

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DOI

10.1016/0925-8388(94)90801-X

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1432-5195

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Skeletal tissue regeneration where can hydrogels

Authors: Liliana S Moreira Teixeira Jennifer Patterson Frank P Luyten
Publish Date: 2014/06/27
Volume: 38, Issue: 9, Pages: 1861-1876
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Abstract

The emerging field of tissue engineering reveals promising approaches for the repair and regeneration of skeletal tissues including the articular cartilage bone and the entire joint Amongst the myriad of biomaterials available to support this strategy hydrogels are highly tissue mimicking substitutes and thus of great potential for the regeneration of functional tissues This review comprises an overview of the novel and most promising hydrogels for articular cartilage osteochondral and bone defect repair Chondro and osteoconductive and instructive hydrogels are presented highlighting successful combinations with inductive signals and cell sources Moreover advantages drawbacks and future perspectives of the role of hydrogels in skeletal regeneration are addressed pointing out the current state of this rising approachThis work is part of Prometheus the KU Leuven RD division for skeletal tissue engineering http//wwwkuleuvenbe/prometheus The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Program FP/2007–2013/ERC Grant Agreement n 249191 from the Research Program of the Research Foundation—Flanders FWO grant n G098211 and postdoctoral mandate—12C8214N and from the special research fund of the KU Leuven GOA/13/017

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