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Title of Journal: International Orthopaedics SICOT

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Abbravation: International Orthopaedics

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Springer Berlin Heidelberg

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10.1007/s40278-015-7136-4

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1432-5195

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Outcomes of radical debridement versus no debridem

Authors: Jun Qian Aierken Rijiepu Bin Zhu Dasheng Tian Lei Chen Juehua Jing
Publish Date: 2016/06/08
Volume: 40, Issue: 10, Pages: 2081-2088
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Abstract

Whether radical debridement is necessary for the treatment of thoracic and lumbar tuberculosis is still questionable The objective of this prospective randomized study was to compare the outcomes of radical debridement versus no debridement for the treatment of thoracic and lumbar tuberculosisSeventyfour thoracic and lumbar tuberculosis patients with a neurological function of grade D and E underwent surgery and received the same chemotherapy regiment from January 2009 to October 2014 All patients were divided into group A and B by taking the drawing of lots In group A radical debridement bone graft and instrumentation were performed Isolated posterior instrumentation without debridement were performed in group B The operative time blood loss visual analogue score VAS erythrocyte sedimentation rate ESR kyphotic angle Frankel grading fusion rate and complications were evaluatedGroup B had a better clinical outcome with regard to the operative time blood loss VAS score first week postoperatively and the ESR value in the third and sixth month postoperatively than group A and the differences between the two groups about those values all presented a significant difference P  005 However no difference was observed between the two groups for the kyphotic angle P = 0088 and fusion rate P = 0164 at the final followup Neurological function of all cases exhibited normal neurological function in the two groups at the final followup Two cases of pulmonary infection and four cases of wound infection in group A No serious complications were observed in group B

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