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Title of Journal: Heart Vessels

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Abbravation: Heart and Vessels

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Springer Japan

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DOI

10.1016/0031-9201(90)90194-3

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1615-2573

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Gender differences in plaque characteristics of cu

Authors: Soe Hee Ann Cai De Jin Gillian Balbir Singh Kyung Hun Lim JaeWook Chung Scot Garg Moo Hyun Kim WangSoo Lee Kyoung Im Cho Sang Wook Kim EunSeok Shin
Publish Date: 2016/02/13
Volume: 31, Issue: 11, Pages: 1767-1775
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Abstract

There is limited research on plaque characteristics of ST elevation myocardial infarction STEMI patients according to the gender and age 280 Consecutive STEMI patients who underwent VHIVUS imaging on culprit before percutaneous coronary intervention PCI were enrolled in this study Women were significantly older than men 698 ± 10 vs 559 ± 113 p  0001 After propensity matching men had higher plaque burden 797 ± 78 vs 737 ± 130  p = 0010 more fibrofatty tissue 128 ± 99 vs 95 ± 68  p = 004 and less dense calcium than women 84 ± 58 vs 123 ± 87  p = 0007 Subgroups dividing by 50 65 75 years old plaque burden was higher in elderly men aged 66–75 years compared to the young men aged less than 50 755 ± 92 vs 684 ± 101  p = 0012 And middle aged men ranged 51–65 years showed significantly more plaque burden at minimal lumen area site than matched aged women 775 ± 80 vs 690 ± 176  p = 0012 Elderly women aged 66–75 years showed significantly more necrotic core 286 ± 73  and dense calcium 149 ± 75  compared to all the younger or matched subgroups of men These differences in plaque composition are blunted in the very elderly of men and women aged over 75 years The findings may explain the gender differences in clinical prognosis in STEMI patients

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