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Title of Journal: J Neurol

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Abbravation: Journal of Neurology

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Springer-Verlag

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DOI

10.1002/cite.200403370

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1432-1459

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Early MRI findings in CreutzfeldtJakob disease

Authors: Marco Onofrj Tommaso Fulgente Domenico Gambi Giorgio Macchi
Publish Date: 1993/07/01
Volume: 240, Issue: 7, Pages: 423-426
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Abstract

We describe the MRI changes preceding the onset of myoclonus in two patients whose postmortem examination confirmed the diagnosis of CreutzfeldtJakob disease CJD MRI showed changes in the striatum early in the course of CJD 2–6 months after the onset of apathy interpreted as depression and 1–2 months before the onset of further clinical symptoms Only in one patient did electroencephalography record the typical triphasic sharpwaves 1 month after MRI

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