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Title of Journal: J Neurol

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Abbravation: Journal of Neurology

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Springer-Verlag

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DOI

10.1007/bf00173140

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1432-1459

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Multiple sclerosis imaging recent advances

Authors: Maria A Rocca Roberta Messina Massimo Filippi
Publish Date: 2012/12/21
Volume: 260, Issue: 3, Pages: 929-935
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Abstract

In this review we summarize advances in knowledge derived from the application of magnetic resonance imaging MRIbased techniques to patients with multiple sclerosis MS published in the Journal of Neurology over the past year We highlight the pivotal role played by conventional MRI techniques for a correct and early diagnosis of this condition and the exclusion of alternative disorders Advanced MR methods have contributed to demonstrating how damage to selected brain structures is related to disease clinical manifestations thus contributing to overcome the wellknown “clinicalradiological” paradox of MS and ameliorating the understanding of the mechanisms underlying the accumulation of irreversible disability Finally we discuss the use of MRI to assess treatment efficacy and optimize therapeutic approaches in this condition

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