Efficacy of Periodontal Disease and Tooth Loss to

Authors: K Inagaki Y Kurosu N Yoshinari T Noguchi E A Krall R I Garcia

Publish Date: 2005/07/14

Volume: 77, Issue: 1, Pages: 9-14

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Abstract

The relationship between oral indicators and bone mineral density BMD has been studied by many investigators with mixed and complex results The purpose of the present crosssectional study was to evaluate the associations of periodontal conditions and tooth loss with metacarpal BMD mBMD in a communitybased cohort and the usefulness of tooth count as a potential screening tool to detect low BMD Subjects were 356 Japanese women 171 premenopausal mean age 379 ± 80 years 185 postmenopausal mean age 633 ± 77 years Periodontal status was evaluated by the Community Periodontal Index of Treatment Needs CPITN mBMD was measured by computerized Xray densitometry The proportion of subjects with periodontitis CPITN 3 or 4 increased as mBMD decreased The odds ratio OR of osteopenia or osteoporosis in relation to periodontitis was 32 95 confidence interval CI 20–53 After adjustment for age and menopausal status the OR was 20 95 CI 11–37 Among postmenopausal women those having fewer than 20 teeth were 16 times more likely to have low mBMD than those having more than 20 teeth chisquare for trend in postmenopausal group 427 P 005 Receiveroperating curve ROC analysis indicated that number of teeth remaining or CPITN score had a greater than 50/50 chance to correctly identify women with osteoporosis or osteopenia but the areas under the curve 072 and 067 respectively are considered less than highly accurate screening tools These results indicate that periodontitis and tooth loss after menopause may be useful indicators of mBMD loss in Japanese womenThe authors would like to acknowledge the assistance of Drs Kazuhiro Noda Hiroyasu Murata Hirokatsu Asai Yoshihiro Hasegawa and Hiroshi Sumi of the Ichinomiya Dental Association for their support This study was supported in part by a GrantinAid for Scientific Research from the Japanese Ministry of Education Science Sports and Culture No 16390616 and the AGU HighTech Research Center Project for Private Universities matching fund subsidy from Ministry of Education Culture Sports Science and Technology 2003–2007 Dr Garcia is supported by NIH Grant K24 DE00419 from the National Institute of Dental and Craniofacial Research

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