Journal Title
Title of Journal: J Nat Med
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Abbravation: Journal of Natural Medicines
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Authors: Michiko Jo Norio Nakamura Nobuko Kakiuchi Katsuko Komatsu Minghua Qui Kumiko Shimotohno Kunitada Shimotohno Masao Hattori
Publish Date: 2006/05/24
Volume: 60, Issue: 3, Pages: 217-224
Abstract
For the purpose of developing novel antihepatitis C virus HCV agents from natural resources 93 Yunnan crude drugs were screened for their inhibitory effects on RNAdependent RNA polymerase RdRp of HCV Although 71 methanol extracts and 50 water extracts inhibited HCVRdRp by more than 50 at a concentration of 50 μg/ml the majority of them contained a high percentage of tannins However methanol extracts of Plumbago zeylanica branch Maytenus fookerii leaf and Huashidancha Y61 branch and leaf and water extracts of Potentilla griffithii whole plant and Salvia yunnanensis underground part having IC50 values of less than 10 μg/ml showed less than 10 tannin content In addition from a methanol extract of Tripterygium hypoglaucum root bark demethylzeylasteral was isolated as a strongly inhibitory substance against HCVRdRp
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- Morinda citrifolia fruit juice prevents ischemic neuronal damage through suppression of the development of post-ischemic glucose intolerance
- A novel steroidal alkaloid from Fritillaria shuchengensis
- Comparative cytotoxicity of 2,3,9-trimethoxypterocarpan in leukemia cell lines (HL-60, Jurkat, Molt-4, and K562) and human peripheral blood mononuclear cells
- Methyl galbanate, a novel inhibitor of nitric oxide production in mouse macrophage RAW264.7 cells
- Patchouli alcohol: in vitro direct anti-influenza virus sesquiterpene in Pogostemon cablin Benth.
- A simple and selective detection method for aristolochic acid in crude drugs using solid-phase extraction
- A simple and selective detection method for aristolochic acid in crude drugs using solid-phase extraction
- Two new flavonoids from Centella asiatica (Linn.)
- Oxomollugin, a potential inhibitor of lipopolysaccharide-induced nitric oxide production including nuclear factor kappa B signals
- Antioxidative activity of the flower of Torenia fournieri
- Cyclic diarylheptanoids as inhibitors of NO production from Acer nikoense
- Morphological, genetic, and chemical polymorphism of Curcuma kwangsiensis
- Chemical and biologically active constituents of Pteris multifida
- Protective effects of an acidic polysaccharide isolated from fruiting bodies of Ganoderma lucidum against murine hepatic injury induced by Propionibacterium acnes and lipopolysaccharide
- Absorptive constituents and their metabolites in drug-containing urine samples from Wuzhishan miniature pigs orally administered with Buyang Huanwu decoction
- Antioxidant activity of red pigments from the lichens Lethariella sernanderi , L. cashmeriana , and L. sinensis
- Three new megastigmanes from the leaves of Annona muricata
- Induction of melanogenesis by 4′- O -methylated flavonoids in B16F10 melanoma cells
- Cesdiurins I–III, steroidal saponins from Cestrum diurnum L.
- Rapid analysis of 56 pesticide residues in natural medicines by GC/MS with negative chemical ionization
- Effect of hydroalcoholic extract of Acorus calamus on tibial and sural nerve transection-induced painful neuropathy in rats
- Effect of hydroalcoholic extract of Acorus calamus on tibial and sural nerve transection-induced painful neuropathy in rats
- Manadodioxans A−E: polyketide endoperoxides from the marine sponge Plakortis bergquistae
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