Authors: Masaki Gushiken Ippei Kagiyama Hikaru Kato Toshiyuki Kuwana Fitje Losung Remy E P Mangindaan Nicole J de Voogd Sachiko Tsukamoto
Publish Date: 2015/05/26
Volume: 69, Issue: 4, Pages: 595-600
Abstract
Five new polyketide endoperoxides manadodioxans A−E were isolated from the marine sponge Plakortis bergquistae Manadodioxan E showed antimicrobial activity against Escherichia coli at 10 μg/disk while its oxo congener manadodioxan D was inactiveWe thank Dr H Kobayashi of the University of Tokyo and Dr H Rotinsulu of Universitas Pembangunan for collecting the sponges This work was supported by GrantsinAid for Scientific Research nos 18406002 25293025 and 26305005 to ST from the Ministry of Education Culture Sports Science and Technology MEXT of Japan
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