Authors: Jun Deguchi Yusuke Motegi Asami Nakata Takahiro Hosoya Hiroshi Morita
Publish Date: 2012/03/29
Volume: 67, Issue: 1, Pages: 234-239
Abstract
We prepared a series of acerogenins A and B derivatives as inhibitors of nitric oxide NO production in vitro Our results suggested that an ester group at a hydroxyl at C2 improved inhibitory effects without cytotoxicity A benzoyl ester derivative of acerogenin C showed the most potent inhibitory activity of NO production from lipopolysaccharideactivated macrophages
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