Authors: Yuko Shigeta Reyes Enciso Takumi Ogawa Werner H Shintaku Glenn T Clark
Publish Date: 2008/04/30
Volume: 12, Issue: 4, Pages: 347-
Abstract
Most obstructive sleep apnea OSA patients are overweight and OSA is substantially more common in obese individuals In morbidly obese patients at least 70 suffer from OSA However the exact mechanism by which obesity causes OSA is unclear The aim of this study is to evaluate the retroglossal airway configuration quantitatively and to make clear the relationship between Body mass index BMI and airway configuration This retrospective study included 15 OSA patients male = 11 female = 4 and 14 normal controls male = 8 female = 6 We studied the airway configuration on an axial slice at the level of the anterior–inferior corner of the second cervical vertebra Maximum anterior–posterior diameter AP and lateral width LW of the airway were measured and the square area SA was calculated The airway crosssection area AWA was also measured and then the AWA/SA ratio was calculated AP LW and AWA were not statistically significantly different between controls and OSA patients On the other hand the AWA/SA ratio in OSA patients was 88 statistically significantly smaller than in controls after adjusting for sex age and BMI In this sample there was a negative correlation between age and the AWA/SA ratio but only in the OSA group The AWA/SA ratio was significantly negatively correlated with OSA status R = −05 p = 0008 after adjusting for BMI and age In this present study we could evaluate the retroglossal airway configuration quantitatively The AWA/SA ratio was correlated with OSA status after adjusting for BMI and ageThe authors have no conflicts of interest Dr Enciso was partially supported by NIDCR grant no 5 K25 DE016391 Dr Ogawa was partially supported by “HighTech Research Center” Project for Private Universities and grant no 18390501 matching fund subsidy from MEXT Ministry of Education Culture Sports Science and Technology
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