Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Sleep Breath

Search In Journal Title:

Abbravation: Sleep and Breathing

Search In Journal Abbravation:

Publisher

Springer Berlin Heidelberg

Search In Publisher:

ISSN

1522-1709

Search In ISSN:
Search In Title Of Papers:

Zopiclone effects on breathing at sleep in stable

Authors: Nils Henrik Holmedahl Britt Øverland Ove Fondenes Ivar Ellingsen Jon Andrew Hardie
Publish Date: 2014/12/13
Volume: 19, Issue: 3, Pages: 921-930
PDF Link

Abstract

More than half of patients with chronic obstructive pulmonary disease COPD experiences sleeprelated problems and about one fourth uses hypnotics regularly We explored what the effect zopiclone a commonly used hypnotic had on nocturnal gas exchange and the apnea/hypopnea frequency in stable COPDRandomized crossover study of 31 ten males inpatients at a pulmonary rehabilitation hospital median age 64 years of which 20 had a forced expiratory volume first second 50  of predicted Subjects investigated in randomized order of either baseline sleep or intervention with 5 mg zopiclone by polysomnography including transcutaneous measurement of carbon dioxide pressure increased ΔPtcCO2Zopiclone increased the mean ΔPtcCO2 from baseline both in rapid eye movement REM sleep nonREM sleep and even in stage N0 awake after sleep onset with a mean SD of 025 040 kPa 022 032 kPa and 014 027 kPa respectively Subjects with sleep hypoventilation as defined by the American Academy of Sleep Medicine increased from 6 subjects 19  to 13 subjects 42  P = 0020 REM sleep minimum oxygen saturation minSpO2 did not change significantly from baseline median interquartile range IQR minSpO2 818 121  to zopiclone sleep median IQR minSpO2 800 120  P = 0766 Interestingly zopiclone reduced the number of apneas/hypopneas per hour AHI in subjects with overlap AHI ≥ 15 with a median difference IQR of −85 78 N = 11 P = 0016PSG hardware and software were provided by ResMed Norway The authors wish to thank the staff at Glittreklinikken for the enthusiastic support and participation in the data collection Financial support was received from the Norwegian ExtraFoundation for Health and Rehabilitation LHL’s Research fund Glittreklinikken and the Norwegian National Centre of Excellence in Home Mechanical Ventilation Minor grants were received from the Norwegian Lung Medicine Society/Takeda Nycomed Major Eckbo’s endowments and the University of Bergen


Keywords:

References


.
Search In Abstract Of Papers:
Other Papers In This Journal:

  1. Effects of resistance training on respiratory function in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
  2. Art competition: Sleep and Breathing 2009
  3. Tailored behavioral medicine intervention for enhanced physical activity and healthy eating in patients with obstructive sleep apnea syndrome and overweight
  4. Age is associated with self-reported sleep bruxism, independently of tooth loss
  5. The effect of CPAP treatment on venous lactate and arterial blood gas among obstructive sleep apnea syndrome patients
  6. How common is sleep-disordered breathing in patients with idiopathic pulmonary fibrosis?
  7. Employee/Employer Interactions and Responsibilities with Special Reference to Genetically Related Sleep Disorders
  8. Cephalometric calcified carotid artery atheromas in patients with obstructive sleep apnea
  9. Validation of blood pressure monitoring using pulse transit time in heart failure patients with Cheyne–Stokes respiration undergoing adaptive servoventilation therapy
  10. A systematic review of central sleep apnea in adult patients with chronic kidney disease
  11. The effect of weight loss on obstructive sleep apnea (OSA) severity and position dependence in the bariatric population
  12. The influence of obesity and obstructive sleep apnea on metabolic hormones
  13. Is obstructive sleep apnea syndrome in children season dependent?
  14. Hemostatic implications of endothelial cell apoptosis in obstructive sleep apnea
  15. Improvement in quality of life after adenotonsillectomy in a child with Prader Willi syndrome
  16. Elevated incidence of sleep apnoea in acromegaly—correlation to disease activity
  17. A promising concept of combination therapy for positional obstructive sleep apnea
  18. Continuous positive airway pressure intolerance associated with elevated nasal resistance is possible mechanism of complex sleep apnea syndrome
  19. Factors that influence CPAP adherence: an overview
  20. Respiratory regulation in narcolepsy
  21. Long-Term Results of Maxillomandibular Advancement Surgery
  22. Correlation between sleep parameters, physical activity and quality of life in somnolent moderate to severe obstructive sleep apnea adult patients
  23. Oral health in patients treated by positive airway pressure for obstructive sleep apnea: a population-based case–control study
  24. Left Ventricular Dysfunction, Pulmonary Hypertension, Obesity, and Sleep Apnea
  25. Correlation between retroglossal airway size and body mass index in OSA and non-OSA patients using cone beam CT imaging
  26. Reply to “Serum high-sensitivity C-reactive protein in patients with obstructive sleep apnea with special reference to metabolic syndrome” by Kawada (Letter to the Editor)
  27. Underdiagnosis of Sleep Apnea Syndrome in U.S. Communities
  28. Longitudinal comparison study of pressure relief (C-Flex™) vs. CPAP in OSA patients
  29. Sleep duration, obesity, and asthma, in Florida adolescents: analysis of data from the Florida Youth Risk Behavior Survey (2009–2013)
  30. Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea
  31. CPAP therapy for patients with sleep apnea and type 2 diabetes mellitus improves control of blood pressure
  32. Influence of gender on continuous positive airway pressure requirements in patients with obstructive sleep apnea syndrome
  33. Process and outcome for international reliability in sleep scoring
  34. Comorbidity modulates non invasive ventilation-induced changes in breath print of obstructive sleep apnea syndrome patients
  35. Variables affecting the change in systemic blood pressure in response to nasal CPAP in obstructive sleep apnea patients
  36. Seasonal trends in sleep-disordered breathing: evidence from Internet search engine query data

Search Result: