Authors: Barbara Strasser Uwe Siebert Wolfgang Schobersberger
Publish Date: 2012/03/07
Volume: 17, Issue: 1, Pages: 217-226
Abstract
Over the last decade the potential use of resistance training RT for patients with chronic obstructive pulmonary disease COPD has gained increasing attention Many COPD patients experience muscle dysfunction and reduced muscle mass primarily as a result of chronic immobilization These symptoms have been associated with reduced exercise tolerance and complaints of fatigue and dyspnea even after minimal exertion This paper presents findings from a systematic review that sought to 1 present a metaanalysis of randomized controlled trials RCT investigating the effects of RT on respiratory function measures in patients with COPD and 2 investigate the existence of a dose–response relationship between intensity duration and frequency of RT and assessed outcomesA systematic literature search of MEDLINE electronic database January 1980 to December 2009 produced a body of research on the effects of RT with a control group in patients with COPD Data analysis involved a random effects metaanalysis in order to determine weighted mean differences with 95 confidence intervals 95 CI for each endpoint All data were analyzed with the software package Review Manager V 4210 of the Cochrane Collaboration 14 RCTs were included in the metaanalysisFindings demonstrated that RT did not substantially increase forced expiratory volume in 1 s In addition the weighted mean difference was 271 of predicted 95 CI −186 to 727 p = 025 or by absolute 008 L 95 CI −003 to 019 p = 014 It appeared that maximum minute ventilation increased by 377 L/min 95 CI −051 to 804 p = 008
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