Journal Title
Title of Journal: Sleep Breath
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Abbravation: Sleep and Breathing
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Publisher
Springer Berlin Heidelberg
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Authors: M C Carra F Thomas A Schmitt B Pannier N Danchin Ph Bouchard
Publish Date: 2015/08/14
Volume: 20, Issue: 1, Pages: 405-411
Abstract
Recent epidemiological evidence suggests that patients with obstructive sleep apnea OSA have an increased risk of periodontal disease Little is known about the oral health of OSA patients treated by continuous or bilevel positive airway pressure CPAP/BiPAP The aim of this populationbased case–control study was to compare oral health variables amount of plaque calculus gingival inflammation and masticatory function between CPAP/BiPAP users and control subjectsThe study population was retrieved from a French cohort examined between 2012 and 2013 at the Centre d’Investigations Préventives et Cliniques of Paris Cases were selected if they reported to be treated by CPAP/BiPAP controls were age gender and BMImatched based on a 12 ratio Univariate and logistic regression analyses were performed for group comparisonsOver a total of 20436 subjects 287 CPAP/BiPAP users mean age SD 576 years 115 763 males who underwent medical and dental examinations were compared with 574 matched controls no OSA no CPAP/BiPAP CPAP/BiPAP users reported significantly higher prevalence of diabetes 156 vs 103 p = 0012 odds ratio OR 168 history of hypertension 365 vs 261 p = 0003 OR 162 cardiovascular diseases 141 vs 88 p = 0029 OR 169 and sleep complaints 59 vs 344 p = 00001 OR 275 CPAP/BiPAP users also showed higher levels of depression and stress compared to controls However no group difference was observed for the amount of dental plaque calculus gingival inflammation and masticatory functionAll authors certify that they have no conflict of interest to disclose in relation to the subject matter or materials discussed in the present study ND received funding and research support from Amgen AstraZeneca Bayer Daiichi Sankyo Sanofi and Eli Lilly He is consultant and speakers’ bureau for Sanofi MSD GSK Pfizer NovoNordisk Sevier Daiichi Sankyp Eli Lilly and Bayer PB received funding and research support from Colgate and Johnson Johnson MCC AS FT and BP have no affiliations with or involvement in any organization or entity with any financial interest
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