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Title of Journal: Sleep Breath

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Abbravation: Sleep and Breathing

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Springer-Verlag

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DOI

10.1007/bf03282568

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1522-1709

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Influence of gender on continuous positive airway

Authors: Gnananandh Jayaraman Hashir Majid Salim Surani Christina Kao Shyam Subramanian
Publish Date: 2010/11/16
Volume: 15, Issue: 4, Pages: 781-784
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Abstract

Gender differences have been noted in key aspects of upper airway physiology and pathophysiology of obstructive sleep apnea OSA We postulate that these will lead to disparities in pharyngeal collapsibility and consequently positive airway pressure requirements of patients with OSAThe study groups were similar with regard to the severity of OSA median apnea–hypopnea index of 34 in men and 24 in women p = 013 The men were older and less obese than the women mean age of 46 and 41 years p = 003 BMI of 42 and 49 kg/m2 p  0001 in men and women respectively Epworth score was similar in the two groups 12 vs11 p = 091 CPAP requirement was higher in men than in women 127 vs 102 p  00001 The effect of gender on CPAP requirement was found to be significant even when confounding variables were accounted for using linear regression

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