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Title of Journal: Int J Hematol

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Abbravation: International Journal of Hematology

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Springer Japan

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DOI

10.1007/s12646-009-0036-z

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1865-3774

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Spinal epidural granulocytic sarcoma in nonleukem

Authors: Darko Antic Srdan Verstovsek Ivo Elezovic Dana Grujicic Mirjana Gotic Jelena Bila Maja Perunicic Ljubomir Jakovic
Publish Date: 2008/12/26
Volume: 89, Issue: 1, Pages: 95-97
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Abstract

A previously healthy 24yearold male presented with a 3month history of progressive backache and weakness in both legs Magnetic resonance imaging of the spine showed a large soft tissue mass infiltrating paraspinal musculature of lumbosacral area sacral laminas last lumbar and all sacral vertebra protruding into the spinal canal and with propagation into pelvis Baseline laboratory data were normal Decompressive laminectomy and tumor removal were performed resulting in neurological improvement Histological examination identified granulocytic sarcoma GS Bone marrow biopsy showed normal findings The patient underwent adjuvant chemotherapy and radiotherapy resulting in the elimination of residual lesion followed by autologous transplant Immediate diagnosis and adequate systematic treatment are essential to achieve optimal results in patients with isolated GS The patient is alive and free of the disease 14 months from the diagnosis

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