Exposure to sunlamps tanning beds and melanoma r

Authors: Kerri M CloughGorr Linda TitusErnstoff Ann E Perry Steven K Spencer Marc S Ernstoff

Publish Date: 2008/02/14

Volume: 19, Issue: 7, Pages: 659-669

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Abstract

Populationbased case–control study of 423 cases of melanoma and 678 controls in the state of New Hampshire Exposure data including sunlamp and tanning bed use were collected by telephone interview Associations were evaluated using logistic regression analysesAbout 17 of participants ever used a sunlamp and most use 89 occurred before 1980 The OR was 139 95 CI 100–196 for ever using a sunlamp 123 95 CI 081–188 for those starting sunlamp use 20 years and 171 95 CI 100–292 for those starting ≥20 years Data suggested increasing risk with number of sunlamp uses and with duration of use tests of trend p = 002 The overall prevalence of tanning bed use was 22 and most use 83 occurred after 1980 The OR was 114 95 CI 080–161 for ever using a tanning bed there was no evidence that risk increased with frequency or duration of use The OR was 196 95 CI 106–361 for having used both devicesResults suggest a modest association between sunlamp use and melanoma risk and increasing risk with greater frequency and duration of use No association with tanning bed use was found but sufficient lag time may not have elapsed to assess a potential effectThis work was supported by grant RO1CA 66032 from the National Cancer Institute and conducted at Dartmouth Medical School This manuscript contains original material that has not been previously presented None of the authors have a conflict of interestWe are grateful to Rebecca A Silliman Professor of Medicine and Public Health and Timothy L Lash Associate Professor of Public Health and Medicine both at Boston University for their informed advice and thoughtful critic of this study We would like to thank the physicians in New Hampshire for their cooperation with this study and the men and women of New Hampshire who generously gave their time to ensure the success of this project

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