Authors: Aluko A Hope Shiriki K Kumanyika Justine Shults William C Holmes
Publish Date: 2010/05/11
Volume: 19, Issue: 7, Pages: 1025-1033
Abstract
Data were analyzed for 87 men and women who provided weight measurements after an initial 10week weight loss program Phase 1 and a subsequent clinical trial to evaluate three weight maintenance approaches Phase 2 over an additional 8 to 18 months HRQoL was assessed using the Short Form SF36 questionnaire Intraperson changes in HRQoL were assessed and analyzed for associations with weight change within each phase Nonparametric bivariable analyses and multivariable linear regression were used in statistical analysesChanges in HRQoL were modest clinically significant intrasubject improvements in SF36 domains of general health and vitality and in the mental component summary score were observed after Phase 1 but were attenuated during Phase 2 Improvements in vitality were significantly associated with greater weight loss in Phase 1 but no HRQoL change scores during Phase 2 were associated with weight change
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