Authors: Uwe Matterne Jochen Schmitt Thomas L Diepgen Christian Apfelbacher
Publish Date: 2011/02/24
Volume: 20, Issue: 8, Pages: 1295-1305
Abstract
Several studies have looked at the relationship between childhood atopic disease and healthrelated quality of life HRQoL but existing research is limited by selected populations small samples or lack to consider each of the three atopic conditions simultaneouslyImpact of 4week and 12month occurrences of the three conditions on HRQoL were analysed by the use of complex sample general linear models alone and adjusted for the other atopic conditions sociodemographics and mental health in a populationbased sample n = 6518 of children and adolescents aged 11–17In univariate analyses total HRQoL was significantly impacted by eczema and hay fever but not asthma with stronger effects for 4week occurrence In multivariate analyses 12month occurrence of hay fever and 4week occurrence of eczema and hay fever significantly impacted on total HRQoL Although most of the variance in HRQoL was explained by mental health independent effects of the atopic conditions remainedAtopic conditions impact HRQoL over and above mental health When analysing the relationship between atopic conditions and HRQoL it is important to consider more immediate versus less immediate effects of the conditions Extent of impairment and the domains affected appear to vary when different time intervals are used
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