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Title of Journal: World J Urol

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Abbravation: World Journal of Urology

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Springer-Verlag

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DOI

10.1002/bem.21929

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1433-8726

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The result of adjuvant chemotherapy for localized

Authors: Atsunari Kawashima Yasutomo Nakai Masashi Nakayama Takeshi Ujike Go Tanigawa Yutaka Ono Akihito Kamoto Tsuyosi Takada Yuichiro Yamaguchi Hitoshi Takayama Kazuo Nishimura Norio Nonomura Akira Tsujimura
Publish Date: 2011/10/09
Volume: 30, Issue: 5, Pages: 701-706
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Abstract

A study population of 93 patients with pT3N0/xM0 UUTC was eligible for this study Clinical features evaluated were sex tumor location adjuvant chemotherapy status tumor pathology histology grade infiltrating growth lymphovascular invasion LVI and cause of death Cancerspecific survival CSS was estimated by Kaplan–Meier method Prognostic factors related to CSS were analyzed by Cox proportional hazards regression model for multivariate analysisIn pT3 patients overall 5year CSS rate was 684 and median CSS time was 31 months range 3–114 months In the adjuvant chemotherapy group 5year CSS rate was 808 whereas 5year CSS rate was 644 in the nonadjuvant chemotherapy group By multivariate analysis adjuvant chemotherapy status was significantly associated with CSS P = 0008 were sex tumor grade tumor histology and LVI presence

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