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Title of Journal: World J Urol

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Abbravation: World Journal of Urology

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Springer Berlin Heidelberg

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DOI

10.1016/0038-1098(89)90186-5

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1433-8726

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Adult inguinoscrotal sarcomas outcome analysis of

Authors: Michael Froehner Rainer Koch Arndt Lossnitzer Rebecca R Schober Markus Schuler Manfred P Wirth
Publish Date: 2013/07/09
Volume: 32, Issue: 2, Pages: 445-451
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Abstract

An updated series of 21 men treated for sarcoma of the inguinoscrotal region at our institution between 1992 and 2012 was analyzed and a systematic review of the literature with metaanalysis of outcome data was performed The review was focused on demographic data survival rates prognostic factors sites of relapse and complete remissions or successful treatments for metastatic diseaseWith only 38  the proportion of highgrade tumors in our sample was lower than reported in the literature and the 10year relapsefree diseasespecific and overall survival rates were favorable with 77 93 and 81  Beside our series twelve studies including 345 patients were identified in the literature The weighed mean 10year relapsefree diseasespecific and overall survival rates were 63 64 and 50  Only in patients with rhabdomyosarcoma durable control of metastatic disease has been reported in more than one case n = 4 Successful treatment in these cases consisted of a combination of complete surgical resection of metastatic lesions subsequent chemotherapy and optional radiotherapyOverall about twothirds of inguinoscrotal sarcomas may be cured In series with a predominance of lowgrade tumors the longterm survival rates in completely excised inguinoscrotal sarcomas may be as favorable as in testicular germ cell tumors Lifelong surveillance is advisable to detect late recurrences

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