Authors: E H Nielsen U FeldtRasmussen L Poulsgaard L Ø Kristensen J Astrup J O Jørgensen P Bjerre M Andersen C Andersen J Jørgensen J Lindholm P Laurberg
Publish Date: 2011/02/19
Volume: 104, Issue: 3, Pages: 755-763
Abstract
We studied the incidence of craniopharyngioma in Denmark during the period 1985–2004 and estimated worldwide incidence rates IR of craniopharyngioma based on a literature review Craniopharyngioma patients diagnosed during the period 1985–2004 were identified from the Danish National Patient Registry the Danish Cancer Registry and regional registries Medical records were reviewed Danish population data were obtained from Statistics Denmark European and World population data were obtained from EU and WHO homepages Prior studies providing data on craniopharyngioma IRs were identified via PubMed and if appropriate were included in a weighted analysis estimating overall and children’s IRs of craniopharyngioma IRs are given as new cases per million per year We identified 189 patients with new verified 162 or probable craniopharyngioma The overall WHO Worldstandardised incidence rate was 186 160–214 for all ages and 214 153–292 for children age 15 years Peak incidence rates were observed in age groups 5–9 and 40–44 years Fifteen prior studies including 1232 craniopharyngioma cases were identified Seven and 11 studies respectively were eligible for weighted allages and childhood population IR analyses yielding summary IRs of 134 124–146 all ages and 144 133–156 children We have provided a detailed survey of the incidence of craniopharyngioma in Denmark during a recent 20year period Overall IR of craniopharyngioma in Denmark was 186 160–214 as compared to 214 153–292 among children Weighted estimates of craniopharyngioma world IRs were 134 124–146 in all ages and 144 133–156 among children
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