Authors: Mériam Koob Nadine Girard Badih Ghattas Slim Fellah Sylviane ConfortGouny Dominique FigarellaBranger Didier Scavarda
Publish Date: 2016/01/05
Volume: 127, Issue: 2, Pages: 345-353
Abstract
Childhood brain tumors show great histological variability The goal of this retrospective study was to assess the diagnostic accuracy of multimodal MR imaging diffusion perfusion MR spectroscopy in the distinction of pediatric brain tumor grades and types Seventysix patients range 1 month to 18 years with brain tumors underwent multimodal MR imaging Tumors were categorized by grade I–IV and by histological type A–H Multivariate statistical analysis was performed to evaluate the diagnostic accuracy of single and combined MR modalities and of single imaging parameters to distinguish the different groups The highest diagnostic accuracy for tumor grading was obtained with diffusion–perfusion 7324 and for tumor typing with diffusion–perfusion–MR spectroscopy 5576 The best diagnostic accuracy was obtained for tumor grading in I and IV and for tumor typing in embryonal tumor and pilocytic astrocytoma Poor accuracy was seen in other grades and types ADC and rADC were the best parameters for tumor grading and typing followed by choline level with an intermediate echo time CBV for grading and Tmax for typing Multiparametric MR imaging can be accurate in determining tumor grades primarily grades I and IV and types mainly pilocytic astrocytomas and embryonal tumors in children
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