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Title of Journal: Eur J Clin Microbiol Infect Dis

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Abbravation: European Journal of Clinical Microbiology & Infectious Diseases

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Springer-Verlag

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DOI

10.1007/s00216-012-6526-1

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1435-4373

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Evaluation of Meridian TRU Legionella® a new rapi

Authors: J P Bruin B M W Diederen
Publish Date: 2012/09/26
Volume: 32, Issue: 3, Pages: 333-334
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Abstract

We evaluated the ability of a new antigen test TRU Legionella® assay Meridian Bioscience Cincinnati OH USA to detect Legionella pneumophila serogroup 1 antigen in urine The results were compared with those obtained with the Binax NOW® urinary antigen test Binax Portland ME USA The sensitivities and specificities were 73  95  confidence interval CI 65 to 81  and 100  respectively for the Meridian TRU Legionella test and 77  95  CI 68 to 84  and 100  respectively for the Binax NOW urinary antigen test The sensitivity of the Meridian TRU Legionella test increased to 81  if tests were reexamined after 60 min of incubation Prolonged incubation did not affect the specificity We conclude that both assays evaluated have similar performance characteristics and are suitable for the rapid diagnosis of Legionnaires’ disease

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