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Title of Journal: Eur J Clin Microbiol Infect Dis

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Abbravation: European Journal of Clinical Microbiology & Infectious Diseases

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Springer Berlin Heidelberg

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DOI

10.1016/0920-5632(91)90202-p

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ISSN

1435-4373

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Serious fungal infections in Canada

Authors: S F Dufresne D C Cole D W Denning D C Sheppard
Publish Date: 2017/02/04
Volume: 36, Issue: 6, Pages: 987-992
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Abstract

There are currently no nationwide epidemiological data on fungal infections in Canada We estimated the burden of serious fungal diseases using literature review and modeling as per a methodology previously described by the LIFE program http//wwwLIFEworldwideorg Among the population of Canada 355 million in 2014 it was estimated that approximately 18 are affected by a serious fungal infection Recurrent vulvovaginal candidiasis severe asthma with fungal sensitization and allergic bronchopulmonary aspergillosis are the most frequent infections with population prevalences of 498688 1403/100000 73344 206/100000 and 61854 174/100000 cases respectively Over 3000 invasive fungal infections are estimated to occur annually with incidences of 2068 cases 58/100000 of invasive candidiasis 566 cases 16/100000 of invasive aspergillosis 252 cases 071/100000 of Pneumocystis pneumonia 99 cases 028/100000 of endemic mycoses and 63 cases 018/100000 of cryptococcosis These estimates warrant validation through more formal epidemiological studies in Canada

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