Authors: Juxian Song Yu Wang Kuansheng Ma Shuguo Zheng Ping Bie Feng Xia Xiaowu Li Jianwei Li Xiaojun Wang Jian Chen
Publish Date: 2015/12/29
Volume: 30, Issue: 10, Pages: 4249-4257
Abstract
In this retrospective study we enrolled 156 patients with a single small HCC with nodular diameters 4 cm and compared recurrencefree survival RFS and overall survival OS between patients treated with LH and control patients treated with RFA n = 78 each The groups were selected according to predefined criteria and matched in terms of their baseline clinical characteristicsDuring a median followup of 312 months the 1 2 and 3year OS rates in the LH group were 962 913 and 841 respectively compared with 962 826 and 788 in the RFA group The corresponding RFS rates were 821 715 and 600 in the LH group and 654 477 and 376 in the RFA group Combined RFS rates were significantly higher in the LH groups P = 0006 but there was no significant difference in OS rates P = 0510 The incidence of postoperative complications was significantly lower in the RFA group 282 vs 103 P = 0004 and operation duration intraoperative blood loss and blood transfusion use of total parenteral nutrition and length of stay as indicators of minimal invasiveness were also significantly better in the RFA groupWe thank the patients who participated in this study for their cooperation and the anonymous reviewers for their helpful comments We also thank Yongkang Zhou for data management and laboratory support This project was financially supported by a clinical research study fund from the First Affiliated Hospital Third Military Medical University China No SWH2014LC23
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