Authors: Pinar Yazici Muhammet Akyuz Hakan Yigitbas Cem Dural Alexis Okoh Nail Aydin Eren Berber
Publish Date: 2016/07/21
Volume: 31, Issue: 3, Pages: 1269-1274
Abstract
Liver resection is the treatment option with the best chance for cure in patients with malignant liver tumors However there are concerns regarding postoperative recovery in elderly patients which may lead to a preference of nonresectional therapies over hepatectomy in this patient population Although laparoscopic liver resection LLR is associated with a faster recovery compared to open hepatectomy there are scant data on how elderly patients tolerate LLR The aim of this study was to analyze the perioperative outcomes of LLR in elderly patients with hepatic malignancies with a comparison to laparoscopic RFA LRFAA retrospective analysis of a prospective database for liver tumors identified a total of 82 patients older than 65 years who underwent laparoscopic treatment of their liver tumors in a single tertiary care center between 2000 and 2014 These patients were equally distributed into LLR and LRFA treatment armsMean age American Society of Anesthesiologists ASA score and tumor type predominantly metastatic colorectal cancer were similar in both groups Patients in the LRFA group had more tumors 21 ± 18 vs 12 ± 06 p 001 whereas tumors were larger in the LLR group 38 ± 16 vs 28 ± 11 cm p 001 Although the operative time 116 vs 214 min p 001 and hospital stay 21 vs 34 days p = 0010 were shorter for the LRFA versus LLR group respectively morbidity 48 vs 73 and mortality 0 vs 0 were similar Local recurrence was significantly higher in the LRFA versus LLR group 29 vs 24 respectively p = 0002 However there was no statistical difference in diseasefree and overall survival between two groups 28 vs 30 and 51 vs 54 months p = 0443 and 0768 respectivelyPinar Yazici Hakan Yigitbas Cem Dural Alexis Okoh Muhammet Akyuz and Nail Aydin have no financial or commercial relationship to disclose that might pose a conflict of interest Eren Berber MD is a consultant to Aesculap Inc and Ethicon with honoraria received for educational talks
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