Authors: Toshiyuki Kosuga Daisuke Ichikawa Shuhei Komatsu Takeshi Kubota Kazuma Okamoto Hirotaka Konishi Atsushi Shiozaki Hitoshi Fujiwara Eigo Otsuji
Publish Date: 2016/08/09
Volume: 31, Issue: 4, Pages: 1667-1674
Abstract
Surgical site infection SSI particularly organ/space SSI remains a clinically important issue even after laparoscopic gastrectomy LG for gastric cancer GC This study aimed to identify specific clinical and surgical factors associated with organ/space SSI after LGThis was a retrospective study of 407 patients who underwent LG for clinical stage I GC SSI was defined according to the National Nosocomial Infection Surveillance System The incidence and treatment outcomes of either incisional or organ/space SSI after LG were examined and the risk factors for each type of SSI were identified using univariate and multivariate analysesOrgan/space SSI was observed in 21 patients 52 while incisional SSI was detected in 18 patients 44 Although no mortality was observed the occurrence of either incisional or organ/space SSI significantly prolonged postoperative hospital stays p = 0000 and 0000 respectively however organ/space SSI required more reoperations and readmissions and eventually longer total hospital stays than incisional SSI p = 0036 Intraabdominal abscess around the pancreas was the main cause of organ/space SSI while no anastomotic leakage was observed Multivariate analyses identified male gender odds ratio OR 3385 95 confidence interval CI 1073–1507 p = 0037 chronic liver disease OR 8897 95 CI 2502–2899 p = 0001 and total gastrectomy TG OR 3817 95 CI 1380–1024 p = 0011 as independent risk factors for organ/space SSI while TG OR 3130 95 CI 1102–8768 p = 0033 and operation time ≥320 min OR 3732 95 CI 1109–1698 p = 0033 were independently associated with incisional SSI
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