Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: World J Surg

Search In Journal Title:

Abbravation: World Journal of Surgery

Search In Journal Abbravation:

Publisher

Springer-Verlag

Search In Publisher:

DOI

10.1002/chin.200526004

Search In DOI:

ISSN

1432-2323

Search In ISSN:
Search In Title Of Papers:

Vascular Endothelial Growth Factor Expression and

Authors: Christian Möbius Hubert J Stein Ingrid Becker Marcus Feith Jörg Theisen Peter Gais Uta Jütting J Rüdiger Siewert
Publish Date: 2004/06/04
Volume: 28, Issue: 7, Pages: 675-679
PDF Link

Abstract

Angiogenesis is essential for tumor growth and metastasis An association between microvessel density a measure of tumor angiogenesis and conventional prognostic variables has been shown for many tumor entities For Barrett’s carcinoma the results are controversial Immature vessels formed in tumors are structurally and functionally different from those in mature vessels The relation between mature and immature vessels as a prognostic factor for Barrett’s carcinoma has not been assessed Specimens from 45 R0resected Barrett’s carcinomas were immunostained for vascular endothelial growth factor VEGF CD 31 and smooth muscle αactin to discriminate between mature and immature vessels VEGF staining was evaluated quantitatively by measuring optical density with a new computerbased program and expressed as a percentage of the staining juvenile placental tissue on control slides The neovascularization coefficient ie the relation between mature and immature vessels was estimated with an interactive analytic computer program The median survival of the study group was 457 months The neovascularization coefficient correlated with the histopathologic classification p 0001 Survival time in patients with a low neovascularization coefficient was significantly better than the survival time in patients with a high neovascularization coefficient p = 0021 VEGF expression did not correlate with clinicopathologic data p 005 or with patient survival p 005 The tumors with a high neovascularization coefficient did not have significantly elevated VEGF expression Based on a strong quantitative computer evaluation program the present study indicates that neovascularization has an important impact on the survival of patients with Barrett’s carcinoma However VEGF does not appear to be the vascular growth factor stimulating neovascularization in Barrett’s carcinoma patients

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Results of Intraoperative Neuromonitoring in Thyroid Surgery and Preoperative Vocal Cord Paralysis
  2. Measures to Prevent Surgical Site Infections: What Surgeons (Should) Do
  3. Role of Somatostatin in the Prevention of Pancreatic Stump-related Morbidity following Elective Pancreaticoduodenectomy in High-risk Patients and Elimination of Surgeon-related Factors: Prospective, Randomized, Controlled Trial
  4. Molecular Genetics of Thyroid Tumors and Surgical Decision-making
  5. Molecular Genetics of Parathyroid Disease
  6. Analysis of 178 Penetrating Stomach and Small Bowel Injuries
  7. Major Perioperative Morbidity Does Not Affect Long-Term Survival in Patients Undergoing Esophagectomy for Cancer of the Esophagus or Gastroesophageal Junction
  8. Plastic and Reconstructive Surgery in Zambia: Epidemiology of 16 Years of Practice
  9. Development of a Large Animal Model for Investigating Resuscitation After Blast and Hemorrhage
  10. Popliteal Vascular Entrapment
  11. Minimally Invasive Versus Open Total Gastrectomy for Gastric Cancer: A Systematic Review and Meta-analysis of Short-Term Outcomes and Completeness of Resection
  12. An Observational Trial for Papillary Thyroid Microcarcinoma in Japanese Patients
  13. Is Pretreatment Endoscopic Biopsy a Good Predictor of Signet Ring Cell Histology in Gastric Carcinoma?
  14. Proceedings of the 4th Annual Meeting of the Alliance for Surgery and Anesthesia Presence (ASAP): Building Sustainable Surgical Systems
  15. Effect of Surgery on Quality of Life with Operable Breast Cancer in Limited Resource Environments: Reply
  16. A Prospective Evaluation of Missed Injuries in Trauma Patients, Before and After Formalising the Trauma Tertiary Survey
  17. Tissue Banking in a Regional Hospital: A Promising Future Concept? First Report on Fresh Frozen Tissue Banking in a Hospital Without an Integrated Institute of Pathology
  18. Glenn’s Urologic Surgery, S.D. Graham, T.E. Keane (eds)
  19. Risk Factors for Early Recurrence of Single Lesion Hepatocellular Carcinoma After Curative Resection
  20. Minimizing Disparities in Surgical Care: A Research Focus for the Future
  21. A Prospective Randomized Single-Blind Control Study of Volume Threshold for Chest Tube Removal Following Lobectomy
  22. Occult Risk of Broken Instruments for Endoscopy-assisted Surgery
  23. Therapeutic Efficacy Comparison of Two Surgical Procedures to Treat Middle Thoracic Esophageal Carcinoma
  24. Intraoperative Diagnosis of Central Compartment Lymph Node Metastasis Predicts Recurrence of Patients with Papillary Thyroid Carcinoma and Clinically Node-Negative Lateral Neck and May Guide Extent of Initial Surgery
  25. Cohort Study of Fever and Leukocytosis as Diagnostic and Prognostic Indicators in Infected Surgical Patients
  26. Navigational Maxillofacial Surgery Using Virtual Models
  27. A Comparative Validation of Primary Surgical Versus Post-neo-adjuvant Chemotherapy Sentinel Lymph Node Biopsy for Stage III Breast Cancers
  28. A Review of Mucinous Cystic Neoplasms of the Pancreas Defined by Ovarian-type Stroma: Clinicopathological Features of 344 Patients
  29. Revisiting Low-Risk Thyroid Papillary Microcarcinomas Resected Without Observation: Was Immediate Surgery Necessary?
  30. Interhospital Transfers of Acute Care Surgery Patients: Should Care for Nontraumatic Surgical Emergencies be Regionalized?
  31. Effect of the Combination of Fibrin Glue and Growth Hormone on Intestinal Anastomoses in a Pig Model of Traumatic Shock Associated with Peritonitis
  32. World Health Organization Global Initiative for Emergency and Essential Surgical Care: 2011 and Beyond
  33. Retrospective Analysis of Nodal Spread Patterns According to Tumor Location in Pathological N2 Non-small Cell Lung Cancer
  34. Living Donor Right Liver Lobe Transplantation With or Without Inclusion of the Middle Hepatic Vein: Analysis of Complications
  35. Can New Inflammatory Markers Improve the Diagnosis of Acute Appendicitis?
  36. Laparoscopıc Fundoplication with Prosthetic Hiatal Closure
  37. Is Rectal Washout Necessary in Anterior Resection for Rectal Cancer? A Prospective Clinical Study
  38. Increase in Bone Mineral Density after Successful Parathyroidectomy for Tertiary Hyperparathyroidism after Renal Transplantation
  39. Clinical Significance of Metastasis to the Central Compartment from Papillary Microcarcinoma of the Thyroid
  40. Two-stage Hepatectomy: Tape It and Hang It, While You Can
  41. Evaluation of Trauma Care Capabilities in Four Countries Using the WHO-IATSIC Guidelines for Essential Trauma Care
  42. Emergency Surgery of the Abdominal Aorta in a Porcine Model: Two Sequential Experiments
  43. Update on Breast Reconstruction Techniques and Indications
  44. What Is a Surgical Complication?
  45. Laparoscopy and Laparoscopic Ultrasonography for Staging Pancreatic Cancer: Critical Appraisal
  46. Predictor for Histological Microvascular Invasion of Hepatocellular Carcinoma: A Lesson from 229 Consecutive Cases of Curative Liver Resection
  47. A Single-center Large-volume Experience in the Surgical Management of Hydatid Disease of the Lung With and Without Extrapulmonary Involvement
  48. Epidemiology of Traumatic Deaths: Comprehensive Population-Based Assessment
  49. Incidence of Perioperative Complications Following Resection of Adrenocortical Carcinoma and Its Association with Long-Term Survival
  50. Trends in Peptic Ulcer Bleeding and Surgical Treatment
  51. Early Presumptive Therapy with Fluconazole for Occult Candida Infection after Gastrointestinal Surgery
  52. A Nodal Positivity Constant: New Perspectives in Lymph Node Evaluation and Colorectal Cancer
  53. Preoperative Ultrasonographic Examination for Lymph Node Metastasis: Usefulness when Designing Lymph Node Dissection for Papillary Microcarcinoma of the Thyroid
  54. Splenic Trauma in Scotland: Demographics and Outcomes
  55. Exclusion of Malignancy in Thyroid Nodules with Indeterminate Fine-Needle Aspiration Cytology After Negative 18 F-Fluorodeoxyglucose Positron Emission Tomography: Interim Analysis
  56. Safety of Nonsteroidal Anti-inflammatory Drugs in Major Gastrointestinal Surgery: A Prospective, Multicenter Cohort Study
  57. Treatment of the Open Abdomen with the Commercially Available Vacuum-Assisted Closure System in Patients with Abdominal Sepsis
  58. Melanoma Controversies: Clinical Significance of Nodal Micrometastases and the Future of Melanoma Vaccines
  59. High-Level CXCR4 Expression Correlates with Brain-Specific Metastasis of Non-Small Cell Lung Cancer
  60. Intraperitoneal Administration of the Angiogenesis Inhibitor Thalidomide Does Not Impair Anastomotic Healing following Large Bowel Resection in a Rabbit Model
  61. Evaluation of Distracting Pain and Clinical Judgment in Cervical Spine Clearance of Trauma Patients
  62. Incisional Hernia Rates After Laparoscopic or Open Abdominal Surgery—A Systematic Review and Meta-Analysis
  63. Effects of Posture and Prolonged Pneumoperitoneum on Hemodynamic Parameters during Laparoscopy
  64. Immunosuppression—Back to the Future
  65. Endoscopic Evaluation of the Quality of the Anastomosis After Esophagectomy with Gastric Tube Reconstruction
  66. Education of the Modern Surgical Resident: Novel Approaches to Learning in the Era of the 80-Hour Workweek
  67. Evolution of Type 2 Diabetes Mellitus in Non Morbid Obese Gastrectomized Patients with Roux en-Y Reconstruction: Retrospective Study
  68. Prognostic Impact of Underlying Liver Fibrosis and Cirrhosis After Curative Resection of Hepatocellular Carcinoma
  69. Virtual Reality Does Not Meet Expectations in a Pilot Study on Multimodal Laparoscopic Surgery Training
  70. Effect of Left Colonic Artery Preservation on Anastomotic Leakage in Laparoscopic Anterior Resection for Middle and Low Rectal Cancer
  71. A Majority of Admitted Patients With Ruptured Abdominal Aortic Aneurysm Undergo and Survive Corrective Treatment: A Population-Based Retrospective Cohort Study
  72. DNA Damage Response Pathways in Tumor Suppression and Cancer Treatment
  73. Evaluation of Office Ultrasound Usage among Australian and New Zealand Breast Surgeons
  74. The Evaluation of Duct-to-mucosal Pancreaticojejunostomy in pancreaticoduodenectomy
  75. Biomarkers for Dysplastic Barrett’s: Ready for Prime Time?
  76. Palpatory Method Used to Identify the Recurrent Laryngeal Nerve during Thyroidectomy
  77. Occurrence and Significance of Odontoid Lateral Mass Interspace Asymmetry in Trauma Patients
  78. Surgical Management of Chronic Wounds in a Buruli Ulcer Endemic Area in Central Africa
  79. Thyroid Surgery in Burkina Faso, West Africa: Experience from a Surgical Help Program
  80. Effects of Preoperative Oral Carbohydrate Supplementation on Postoperative Metabolic Stress Response of Patients Undergoing Elective Abdominal Surgery
  81. Study on the Use of T-tube for Patients with Persistent Duodenal Fistula: Is It Useful?
  82. Risk Factors for Complications After Laparoscopic Surgery in Colorectal Cancer Patients: Experience of 401 Cases at a Single Institution
  83. Aluminum Overload Hampers Symptom Improvement Following Parathyroidectomy for Secondary Hyperparathyroidism
  84. Subtotal Parathyroidectomy in Renal Failure: Still Needed after All These Years
  85. Long-Term Outcomes of Abdominal Wall Reconstruction. What are the Real Numbers?
  86. Airtight Tracheocutaneostomy After Window Resection of the Trachea for Invasive Papillary Thyroid Carcinoma: Experience of 109 Cases
  87. Reference Accuracy in the General Surgery Literature
  88. Thyroid Nodules ≥4 cm: Can Ultrasound and Cytology Reliably Exclude Cancer? Reply
  89. Petrous Carotid Artery’s In Situ Bypass: Anatomic Study
  90. Surgical Treatment of Barrett’s Esophagus: 1980-2003
  91. Testicular and Paratesticular Pathology in Children: a 12-Year Histopathological Review
  92. Prophylactic Antibiotics in Chest Trauma: A Meta-analysis of High-quality Studies
  93. Minimally Invasive Surgery for Gastric Cancer: The Future Standard of Care
  94. Augmented versus Virtual Reality Laparoscopic Simulation: What Is the Difference?
  95. Experience with Porcine Acellular Dermal Collagen Implant in One-stage Tension-free Reconstruction of Acute and Chronic Abdominal Wall Defects
  96. Level VI Lymph Node Dissection Does Not Decrease Radioiodine Uptake in Patients Undergoing Radioiodine Ablation for Differentiated Thyroid Cancer
  97. Emergency Department Thoracotomy: Survival of the Least Expected
  98. Role of Fibrin Glue in the Prevention of Cervical Leakage and Strictures After Esophageal Reconstruction of Caustic Injury
  99. Patients’ Preferences for Surgical Management of Esophageal Cancer: A Discrete Choice Experiment
  100. Mixed-Methods Assessment of Trauma and Acute Care Surgical Quality Improvement Programs in Peru
  101. Surgical Outcome of Abdominoperineal Resection for Low Rectal Cancer in a Nigerian Tertiary Institution
  102. Distinct Recurrence Pattern and Outcome of Adenocarcinoma of the Gastric Cardia in Comparison with Carcinoma of Other Regions of the Stomach
  103. Laparoscopic Lymphatic Mapping and Sentinel Node Biopsies for Early-stage Gastric Cancer: The Cause of False Negativity
  104. Metabolic Assessment
  105. MERCI for Improving Quality of Surgical Care at No Cost: Reply
  106. Must Breast Care Delivery Models from Resource-Rich Environments be Applied to Resource-Limited Environments?
  107. Open Repair of AAA in a High Volume Center
  108. Evaluation of 64-Channel Contrast-Enhanced Multi-detector Row Computed Tomography for Preoperative N Staging in cT2-4 Gastric Carcinoma
  109. Transthoracic Versus Transhiatal Esophagectomy for Esophageal Carcinoma: Experience from a Single Tertiary Care Institution
  110. Surgical Treatment of Iatrogenic Lesions of the Proximal Common Bile Duct
  111. Henna as a Durable Preoperative Skin Marker
  112. Prognostic Significance of Extrathyroid Extension of Papillary Thyroid Carcinoma: Massive but Not Minimal Extension Affects the Relapse-free Survival
  113. Relation of Cytokines to Vasodilation after Coronary Artery Bypass Grafting
  114. Prognostic Significance of Extrathyroid Extension of Papillary Thyroid Carcinoma: Massive but Not Minimal Extension Affects the Relapse-free Survival
  115. Desmoplastic Reaction Influences Pancreatic Cancer Growth Behavior
  116. One-stage Transthoracic Operation for the Treatment of Right Lung and Liver Hydatid Cysts
  117. Development and Validation of a Surgical Workload Measure: The Surgery Task Load Index (SURG-TLX)
Search Result: