Authors: Julián Alberto SaldañaCortés Francisco LariosArceo Emilio PrietoDíazChávez Eliseo Portilla De Buen Salvador GonzálezMercado Andrea Socorro AlvarezVillaseñor Manuel Rodrigo PrietoAldape Clotilde FuentesOrozco Alejandro GonzálezOjeda
Publish Date: 2009/02/21
Volume: 33, Issue: 5, Pages: 986-993
Abstract
The colon is the organ most commonly used for esophageal reconstruction after severe caustic injury Complications of cervical anastomosis are very common Fibrin sealant may reduce the incidence of complications in this highrisk anastomosis The purpose of the present study was to assess the role of fibrin glue in the prevention of leakage and stricture at cervical coloesophageal anastomoses in children treated with esophageal reconstruction after caustic injuryThis was a case–control study of children with caustic esophageal injury treated surgically with esophageal reconstruction over a 10year period In the study group 3–4 ml of fibrin glue was placed over the anastomosis The following variables were assessed age sex weight leakage or stricture at the cervical anastomosis morbidity and mortalityThe study group included 14 children and the control group included 24 children There were no differences in the distributions of sex age anthropometric variables or preoperative laboratory test results All children underwent esophageal replacement with colon substitution through the retrosternal space Dehiscence and leakage at the cervical anastomosis were observed in 50 of children in the control group and 285 of children in the study group P = 017 Strictures were observed in 715 of the study group and 208 of the control group and 5 and 17 children respectively developed cervical complications P = 003 There were no differences in major complications and mortality was similar in the two groups P = 060
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