Authors: Marco von Strauss und Torney Ulrich Güller Farid Rezaeian Philippe Brosi Luigi Terracciano Markus Zuber
Publish Date: 2012/05/26
Volume: 36, Issue: 10, Pages: 2300-2304
Abstract
Vital tissue provided by fresh frozen tissue banking is often required for genetic tumor profiling and tailored therapies However the potential patient benefits of fresh frozen tissue banking are currently limited to university hospitals The objective of the present pilot study—the first one in the literature—was to evaluate whether fresh frozen tissue banking is feasible in a regional hospital without an integrated institute of pathologyPatients with resectable breast and colon cancer were included in this prospective study Both malignant and healthy tissue were sampled using isopentanbased snapfreezing 1 h after tumor resection and stored at −80 °C before transfer to the main tissue bank of a University institute of pathologyThe initial costs to set up tissue banking were 35662 US Furthermore the running costs are 1250 US yearly During the first 13 months 43 samples nine samples of breast cancer and 34 samples of colon cancer were collected from 41 patients Based on the pathology reports there was no interference with standard histopathologic analyses due to the sample collectionThis is the first report in the literature providing evidence that tissue banking in a regional hospital without an integrated institute of pathology is feasible The interesting findings of the present pilot study must be confirmed by larger investigations
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