Authors: Koya Hida Takashi Yamaguchi Hiroaki Hata Hiroya Kuroyanagi Satoshi Nagayama Harue Tada Satoshi Teramukai Masanori Fukushima Kinya Koizumi Yoshiharu Sakai
Publish Date: 2009/06/09
Volume: 33, Issue: 8, Pages: 1733-1740
Abstract
Clinical data were reviewed for 401 consecutive unselected colorectal cancer patients who underwent laparoscopic surgery at Kyoto Medical Center between 1998 and 2005 The outcome variable was incidence of postoperative complications Using logistic regression analysis 58 background clinical preoperative and intraoperative factors were assessed as potential predictors of complicationsThe set of independent protective factors that had the greatest influence on the incidence of local complications after colon surgery was as follows cefmetazole use for prophylaxis versus oral only adjusted odds ratio OR 018 95 confidence interval CI 006–054 high operative infusion rate per ml/min OR 082 95 CI 070–095 regular laxative use OR 033 95 CI 012–079 and doublestapled anastomosis versus handsewn OR 015 95 CI 003–083 Independent risk factors for local complications after rectal surgery were abdominoperineal resection versus low anterior resection OR 484 95 CI 164–149 long operative time per hour OR 155 95 CI 111–223 and history of heart disease OR 518 95 CI 134–215 The occurrence of complications was not found to be associated with overall survival in this studyWe identified intraoperative management such as low operative infusion rate is one of the independent significant risk factors for complications after laparoscopic surgery for colorectal cancer in addition to patient characteristics and surgical procedure
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