Authors: Nadeem UlNazeer Kawoosa Abdul Majeed Dar Mukand Lal Sharma Abdul Gani Ahangar Ghulam Nabi Lone Mohammad Akbar Bhat Shyam Singh
Publish Date: 2011/03/08
Volume: 35, Issue: 6, Pages: 1296-1302
Abstract
In this retrospective study 382 patients with carcinoma of the midtodistal esophagus underwent transthoracic or transhiatal esophagectomy Early morbidity and mortality were compared Principal endpoints were diseasefree survival DFS and overall survival OSA total of 177 patients underwent transthoracic esophagectomy and 205 patients underwent transhiatal esophagectomy Demographic characteristics and characteristics of the tumor were similar in the two groups Perioperative and postoperative morbidity was higher after transhiatal esophagectomy Inhospital mortality was also higher after transhiatal esophagectomy The median followup was 43 years Estimated 3year DFS rates were 4463 and 3121 whereas the 3year OS rates were 5706 and 4146 for the transthoracic and transhiatal groups respectively statistically significant Also the estimated 5year DFS rates were 2655 and 2146 whereas the 5year OS rates were 3276 and 3024 for the transthoracic and transhiatal groups respectively statistically not significantTranshiatal esophagectomy was associated with higher perioperative and postoperative morbidity and inhospital mortality than transthoracic esophagectomy The DFS and OS were higher in the transthoracic group and were statistically significant at 3 years but statistically insignificant at 5 years
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