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Title of Journal: World J Microbiol Biotechnol

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Abbravation: World Journal of Microbiology and Biotechnology

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Springer Netherlands

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DOI

10.1007/bf02463437

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1573-0972

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Characterization and selection of Emphasis Type="

Authors: Min Zhang Xiaomin Hang Xiaobing Fan Daotang Li Hong Yang
Publish Date: 2007/06/02
Volume: 24, Issue: 1, Pages: 7-14
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Abstract

Fourteen Lactobacillus strains of six species were investigated with their characteristics of bile salt tolerance deconjugation of sodium taurocholate and cholesterol removal in the spent broth Meanwhile a coprecipitation curve of cholesterol with cholic acid at concentrations ranged 00–60 μM/ml was involved in the evaluation of cholesterol removal Results demonstrated that both coprecipitation and assimilation effects contributed to cholesterol removal during the incubation of these Lactobacillus strains It was also indicated that the supplementation of bile salts influenced the cholesterol removal not only as an essential factor related to coprecipitation but also a critical condition for cholesterol assimilation Out of all strains tested four L plantarum strains LS12 LS31 Lp501 and Lp529 exhibited a high ability of cholesterol assimilation maximum 2076 μg/ml deconjugation of sodium taurocholate maximum 500 μM/ml and bile tolerance They could be further studied and used as potential probiotics strains to reduce serum cholesterol in humans

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