Authors: Shunrou Fujiwara Makoto Sasaki Yoshiyuki Kanbara Takashi Inoue Ryonoshin Hirooka Akira Ogawa
Publish Date: 2007/10/16
Volume: 50, Issue: 2, Pages: 131-136
Abstract
We examined 20 healthy volunteers by conventional DTI with a voxel size of 16 × 16 × 30 mm and by highresolution DTI with a voxel size of 16 × 16 × 16 mm and generated tractographs of three limbic nerve bundles the fornix cingulum and uncinate fasciculus We visually assessed whether these bundles reached their targets and compared their diffusion parameters between the two techniquesThe entire pathways of the fornix cingulum and uncinate fasciculus were more readily visualized by highresolution DTI than by conventional DTI Among these the fimbria of the fornix and the uncinate fasciculus adjacent to the temporal pole were identified more frequently by highresolution DTI visualization rate 83 and 100 respectively than by conventional DTI visualization rate 63 and 83 respectively at a statistical significance of P 005 and P 001 respectively Fractional anisotropy values in the fornix cingulum and uncinate fasciculus by highresolution DTI were significantly higher than those by conventional DTI P 001 in contrast the apparent diffusion coefficient values of all these fibers except that of the fornix remained unchanged between the two techniques
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