Authors: Natalia Yakunina Eun Kyoung Kang Tae Su Kim JiHoon Min Sam Soo Kim EuiCheol Nam
Publish Date: 2015/07/21
Volume: 57, Issue: 10, Pages: 1063-1073
Abstract
Although the effects of scanner background noise SBN during functional magnetic resonance imaging fMRI have been extensively investigated for the brain regions involved in auditory processing its impact on other types of intrinsic brain activity has largely been neglected The present study evaluated the influence of SBN on a number of intrinsic connectivity networks ICNs during auditory stimulation by comparing the results obtained using sparse temporal acquisition STA with those using continuous acquisition CAFourteen healthy subjects were presented with classical music pieces in a block paradigm during two sessions of STA and CA A volumematched CA dataset CAm was generated by subsampling the CA dataset to temporally match it with the STA data Independent component analysis was performed on the concatenated STA–CAm datasets and voxel data time courses power spectra and functional connectivity were comparedThe ICA revealed 19 ICNs the auditory default mode salience and frontoparietal networks showed greater activity in the STA The spectral peaks in 17 networks corresponded to the stimulation cycles in the STA while only five networks displayed this correspondence in the CA The dorsal default mode and salience networks exhibited stronger correlations with the stimulus waveform in the STASBN appeared to influence not only the areas of auditory response but also the majority of other ICNs including attention and sensory networks Therefore SBN should be regarded as a serious nuisance factor during fMRI studies investigating intrinsic brain activity under external stimulation or task loadsWe declare that all human and animal studies have been approved by the Kangwon National University Hospital Institutional Review Board and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments We declare that all patients gave informed consent prior to inclusion in this study
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